Breast cancer links to parabens

Breast Cancer
In 2003, Dr. Philippa Darbre showed that there was parabens (a preservative used in deodorants and a vast array of toiletries and personal care products - even so-called ’Green’ or all-natural ones) in breast tissue. The Cosmetics industry rubbished the research saying there were no control groups, so she did the research again in 2004. This time they said ’Ok, but who says it causes the breast cancer?’ In 2012 she shows that parabens is present in breast cancer tissue at four times the levels of 2003 and it is coming from multiple sources. (In 2013 Darbre went on to show parabens was causal; she also found higher levels of Aluminum compounds in ducts in breast cancer patients. In 2016, aluminium was shown to be causal. Aluminium is found in ant-acids, antiperspirants and vaccines). The research is ignord by big charities such as Cancer Research UK and The American Cancer Association. Here is the 2012 study, presented by Professor Philippa Darbre.

The good news? You can rid your body of parabens and phthalates. Whereas just 8 days usage shows a build up of quite large concentrations, changing to toxin-free toiletry and personal care products should see you ’Clean’ in less than 30 days, according to an American study.
Go To: Live Clean with toxin-free products
Parabens in Breast Tissue not limited to women who have used underarm products.


New research (Professor Philippa D. Darbre, Jan 2012, University of Reading) into the potential link between parabens and breast cancer has found traces of the chemicals in breast tissue samples from all of the women in the study. Parabens are commonly used as preservatives in cosmetics, food products and pharmaceuticals. As the research shows that parabens are measurable in the tissue of women who do not use underarm cosmetics, the parabens must enter the breast from other sources as well.


Breast tissue samples were taken from 40 women, with the results showing that all of the women had at least one paraben in their tissue. The research, published in the Journal of Applied Toxicology, was a collaborative study led by Dr. Philippa Darbre, University of Reading and Mr Lester Barr, University Hospital of South Manchester.


The research team studied tissue samples from 40 women undergoing mastectomies between 2005 and 2008 for first primary breast cancer in England. In total, 160 samples were collected, four from each woman, covering serial locations from the samples were collected, four from each woman, covering serial locations from the axilla (nearest the armpit) to the sternum (breast bone). 99% of the tissue samples contained at least one paraben and 60% of the samples had five.
A number of studies since 1998 have raised concerns about the potential role of parabens in breast cancer as these chemicals possess oestrogenic properties and oestrogen is known to play a central role in the development, growth and progression oestrogen is known to play a central role in the development, growth and progression of breast cancer. In particular, a link was proposed between the disproportionate incidence of breast cancer in the upper outer quadrant of the breast and oestrogenic incidence of breast cancer in the upper outer quadrant of the breast and oestrogenic 

"Our study appears to confirm the view that there is no simple cause and effect
relationship between parabens in underarm products and breast cancer," said Mr
Lester Barr, consultant surgeon at the University Hospital of South Manchester and Chairman of the Genesis Breast Cancer Prevention Appeal, which part sponsored the study.


"The intriguing discovery that parabens are present even in women who have never used underarm products raises the question: Where have these chemicals come from?"


Key findings of the study included:

One or more paraben esters were detected in 158 of the 160 samples studied
(99%) and 96 of the samples (60%) contained all five of the most common
paraben esters.
The overall median value for total parabens in the breast tissue was 85.5 ng/g - one billionth of a gram of parabens per gram of breast tissue - ranging from 0 ng/g to 5134.5 ng/g. This level was four times higher than the 20.6 ng/g recorded by a smaller study in 2004.
Overall median values for the individual parabens were highest for npropylparaben (16.8 ng/g) and methylparaben (16.6 ng/g), with lower levels for nbutylparaben (5.8 ng/g), ethylparaben (3.4 ng/g) and isobutylparaben (2.1 ng/g).
There was a disproportionate incidence of breast cancer in the upper outer
quadrant nearest the armpit and significantly higher levels of n-propylparaben
were detected in the axilla region, closest to the armpit, than in the mid or medialregions. The other four parabens were equally distributed across all parts of the breast.
The fact that parabens were detected in the majority of the breast tissue samples cannot be taken to imply that they actually caused breast cancer in the 40 women studied, said Dr Philippa Darbre, Reader in Oncology at the University of Reading, who also led the 2004 study. However, the fact that parabens were present in so many of the breast tissue samples does justify further investigation.


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