In a study by Dr. Pier Paolo Pandolfi and a team from Beth Israel Deaconess Medical Center (BIDMC), people with prostate cancer who had high levels of bad fat in their blood were more likely to have metastases develop and survive less.
Chris Woollams, former Oxford University Biochemist and a founder of CANCERactive said, “Actually, we all knew this already, didn’t we? For me, as soon as the LDL and triglyceride levels start to increase in people with prostate cancer, we know it is coming back with a vengeance. The reason was covered in research about six months ago. Cancer cells are inflamed and sticky. A turned on gene then allows them to pick up a fatty ‘coat’ and evade the immune system as they spread round the body. This is why we advocate a good fat Rainbow Diet, exercise and a high vegetable diet.”.
This latest study found that two genes, PTEN and PML, were absent in prostate cancer that metastasised, and this allowed the cancer cells to even make their own fat and spread. It may be that a simple fat-blocking drug could stop prostate cancer spreading - perhaps atorvastatin, already used by some oncologists to cut fat in some people with metastatic cancer?” added Woollams.
"Worryingly, new research shows that androgen-inhibiting drugs like Zolodex, actually increase fat levels in the blood".
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