Pathogens found in upper reproductive tract in ovarian cancer

Pathogens found in upper reproductive tract in ovarian cancer
Pathogens have been found in the upper reproductive tract of women with ovarian cancer; and there seem to be different bacteria in the Fallopian tubes and ovaries; this coincides with research suggesting that up to 70% of ovarian cancer may originate in the Fallopian tubes.

Scientists at University of North Carolina Lineberger Comprehensive Cancer Centre have found pathogens in the Upper Reproductive Tract of women with epithelial ovarian cancer. The tract was previously thought to be sterile.

Importantly, the bacterial composition of the tract (fallopian tubes, ovaries) was completely different in healthy women to those with cancer. The scientists were led by Dr. Wendy Brewster.

Researchers used genetic sequencing to study the types of bacteria present and even found different bacteria present in the fallopian tubes and the ovaries.

Chris Woollams, founder of CANCERactive and ex-Oxford University Biochemist said, “The Professor at UNC Lineberger said that this place is essential to the beginning of life and so you wouldn’t expect to find bacteria, let alone pathogens there! Clearly more work is needed but this could have huge implications in all manner of illnesses from birth defects and autism to ovarian cancer. The questions in ovarian cancer are simple: Do these pathogens influence the development of the cancer and thereafter the aggression? Perhaps the presence of pathogens is why, at CANCERactive, we have seen a significant benefit from the use of herbs like artemisinin with ovarian cancer patients.”

Go to: Review - Artemisinin kills pathogens

Researchers are saying that these findings could even provide an early detection method for ovarian cancer.
In a second study (2), this time from Johns Hopkins Kimmel Cancer Center, scientists have shown that in serous ovarian cancer, the origins may well be in lesions in the fallopian tubes and these lesions may have formed years earlier.
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